"Ladies' Revenge" tells the story of a female assassin, Chanel (played by Stephy Tang), who has been married for ten years and believes that her husband is faithful to her husband. A female snitch, Dior (played by Chrissie Chau), has just been dating for ten years and lives a sweet life. One day, the two women found out that their partners had a third party. After a thorough investigation, they found out that it was each other! The two planned to meet and kill each other, but on the day of the meeting, they found that the jerk was preparing to have a tryst with another woman, Hermes (played by Gaile Lok), in the hotel. The two decided to enter the hotel and kill the couple, but they didn't expect that everything was a trap set by the jerk, who was determined to catch all three women. The three women had no way out and were forced to take ultimate revenge, vowing to kill the jerk.