Nick (Aaron Eckhart) is the spokesperson for the world's most profitable and controversial industry - the tobacco industry. Every day, he not only has to persuade people to smoke like a salesman, but also has to deal with protests from anti-smoking groups, environmental groups and scientific groups in various ways, and try his best to maximize the interests of the tobacco industry in the government and senators. Nick also has two close friends - Polly (Maria Bello), who represents the wine industry, and Bobby (David Koechner), who represents the arms industry. The same industry nature makes the three of them close friends who can talk about anything. They often exchange tips on how to deal with protests from various groups such as environmental groups, and how to deal with the government and senators. On the stage where politics and business intersect, they staged one good show after another.