Jay (Jason Mewes) and Bob (Kevin Smith) have been connected to convenience stores since they were placed side by side at the door of a convenience store by their mother when they were babies. However, the store owner couldn't stand the two of them hanging around outside the store all day, so he called the police to expel them. Jay and Bob's bad luck wasn't over yet. A movie adapted from a comic book with them as the protagonists was about to start filming. In addition to the fact that the film company didn't give them a penny, the Internet was full of abuse and ridicule against them. The angry duo decided to rush to Hollywood from New Jersey to stop the filming of the movie. On the way, the two of them got a ride from four beauties, including animal protectionist Jester. Jay was obsessed with Jester and agreed to help steal the orangutans used in experiments. Who knew that the four women were actually jewel thieves? After Jay and Bob took the orangutan out, they were identified as terrorists by the police. Two people and an orangutan continued to move towards Hollywood amid the police blockade...