This film tells the story of a group of medical workers in the Department of Neurosurgery of Jiangzhou Yunshan Hospital. The eldest brother Liu Chenxi (played by Zhang Jiayi) is not only an excellent doctor, but also a decent person, but his daughter Nan Nan suffers from congenital renal failure. He and his wife have been waiting for a kidney source for his daughter's surgery. The second brother Huo Simiao (played by Wu Xiubo) is a descendant of a meritorious official. He is usually humorous, but meticulous on the operating table. By chance, he met the actress Huang Jingjing (played by Han Yuqin) who took her mother to see a doctor, and the two began to communicate about their illness. When Han's mother was discharged from the hospital, Huang Jingjing had become his VIP. Compared with Huo Simiao's success in love, the older leftover woman Mei Xiaohu (played by Hai Qing) is more sympathetic. She and Huo Simiao have been buddies for many years, often flirting, but maintaining a pure friendship. Zheng Aiping is a rookie who happens to meet the young nurse Zhang Xiaolei (played by Yang Zi) while seeing patients, and the two fall in love... This group of medical staff faces the test of life and death every day. Under the influence and infection of benevolence, benevolence, and benevolence, they experience all kinds of life, joys and sorrows.