During the reign of Emperor Xuan of the Western Han Dynasty, Lady Wang and Lady Chunyu were both female doctors in the harem. Later, they were used, and one committed suicide and the other was beheaded. Lady Chunyu's daughter Chunyu Yao (played by Sang Yehong) witnessed the tragic deaths of her mother and sister, and thus planted the seeds of hatred for Lady Wang's daughter Wang Zhengjun (played by Yuan Li). Fifteen years later, the two little girls of that year have grown into graceful girls. Wang Zhengjun and Chunyu Yao, who changed her name to Fu Yao, were both selected as family members. The family members of the same period also included Feng Yuan (played by Sun Qian), Wang Zhaojun (played by Bai Qinglin), and Li Yuaner (played by Shi Xiaoqun). By chance, the five people met an old woman who predicted that a queen would be born among the five girls. From then on, the five girls buried their own thoughts in their hearts... There is only one queen's throne, who is the lucky one? Can the hatred buried in those years be resolved?