The violence and mystery of tornadoes have attracted a large number of scientists to conduct in-depth research. Going deep into the middle of a storm is the most dangerous behavior, but it is also the most effective way to explore tornadoes. Joe (Helen Hunt) and her divorced husband Bill (Bill Paxton) are such scientists who "dance with dragons". Even though their relationship has broken down and Bill has found a new lover, they are obsessed with tornado research and decide to chase a hurricane in Oklahoma together and put the newly developed detector "Dorothy" in the center of the tornado to collect data. They drive a dilapidated truck and lead the storm chasing team to the most dangerous place. At the same time, another well-equipped team also drove in this direction, led by Juna (Cary Elwes), and competed with Joe in the storm chasing action. On one side is Joe, who shares the same ideals, and on the other side is his new girlfriend who is afraid of a thrilling life. How does Bill choose his emotional path again in the process of chasing the storm? More importantly, facing powerful opponents and a tornado that could bury them at any time, how can Joe and Bill realize their dream of chasing the wind?