The world setting of this drama is that ordinary humans and anthropomorphic animals live together. Except for their appearance, these animals are no different from humans. Bojack the Horseman (voiced by Will Arnett) is a middle-aged out-of-date star horse. The TV series "Horselike Pony" starring him when he was young was all the rage. Now he is an out-of-date star who no one cares about. He lives with Todd (voiced by Aaron Paul) in a villa in LA. In order to regroup, Bojack is urged by his agent and ex-girlfriend Princess Caroline (voiced by Amy Sedaris) to publish an autobiography. This autobiography written by Diane (voiced by Alison Brie) was a big hit as soon as it came out. Bojack returned to the audience's attention and was able to play the leading role in a popular movie. Can Bojack, who has been in a daze for many years, adapt to the new life?