Three stories about dogs, three sad lives. Octava (Gael Garcia Bernal) lives with his mother, brother and sister-in-law. His brother Amilo (Marco Perez) fools around with women, works in a supermarket during the day and robs supermarkets at night. He is very rude to his wife Susanna (Vanessa Bauche) and children. Octava gradually falls in love with Susanna. In order to elope with Susanna, he takes his dog "Goofy" to participate in underground dog fighting competitions and wins a lot of money. Who knows, when the day of the agreed elopement is approaching, Amilo and Susanna leave with the children and take away the money he has saved hard. The exasperated Octava invites his old rival to play the last game. The opponent loses red-eyed and shoots "Goofy". Octava stabs his opponent, drives away, and has a car accident. His life and his family's life have changed since then. The person who collided with Octava was the supermodel Valeria (Goya Toledo), whose lover Daniel (Alvaro Guerrero) had just left his wife and they began to live together. The car accident had a great impact on her career. The pet dog "Mickey" that depended on each other fell under the floor, which severely hit her spirit and put her life in trouble. At the scene of the car accident, the homeless Martin picked up "Goofy". In his early years, Martin abandoned his wife and daughter to join the guerrillas in order to pursue his ideals. After being released from prison, he became a professional killer, but he still had the dream of being an ordinary father and hoped to be forgiven by his daughter. By chance, he had the opportunity to meet his daughter, but he couldn't face it.