Young and capable Miranda (Halle Berry) is an accomplished criminal psychologist. She and her husband run a mental treatment institution together. Both of them are very successful in life and career. However, Miranda, who has always been rational, also encountered a difficult opponent. One of her patients, Chloe (Penélope Cruz), was imprisoned for murdering her stepfather. Chloe often indulges in unrealistic fantasies, which troubles Miranda. On a rainy night, Miranda almost hit a little girl on her way home, and then something incredible happened. When she woke up from a coma, she found herself in a mental hospital and had to face the charge of murdering her husband. Miranda tried every means to prove her innocence, and in the process she also discovered the terrifying and dark truth... The film won the 2004 Youth Choice Award for Best Actress (Halle Berry).