The story takes place in the middle of the Ming Dynasty. Jinyiwei Yang Ao (played by Peng Jingci) and imperial physician Li Heling (played by Huang Zhizhong) were originally brothers from the same school. Because Yang Ao fell in love with his senior brother Heling's fiancée Nishang (played by Lu Yi), he framed his senior brother for raping and killing Hui Fei. In order to save Li Heling, Nishang was forced to marry Yang Ao. Li Heling had no choice but to leave his hometown and fled to Yuancang County, Shanxi to open a medical clinic to make a living. Many years later, due to a bizarre case, he met and became friends with Yuancang County Magistrate Liu Fuxing (played by Zhang Weijian), and they jointly solved many suspicious cases. In a murder case, the mistress of Fan Tai (played by Fang Zhenhua), a subordinate of Yang Ao, was seized, and from her, the truth about Yang Ao's frame-up was learned. Heling went to Beijing to ask the emperor (played by Zong Fengyan) to redress himself, and got the full help of his old love Nishang. Yang Ao killed Nishang in anger. He Ling teamed up with Fuxing to get rid of Yang Ao, the evil star, and declined the good job of the chief imperial physician, and returned to the arena with Fuxing...