The "human flesh" technology in the Internet age is usually a weapon for entertaining the public, but unfortunately, it can also become a tool for killing. After learning that she had cancer, Ye Lanqiu (Gao Yuanyuan), secretary of the chairman of a listed company, got on a bus in despair. She was immersed in astonishment and fear, and refused to give up her seat to an old man on the bus, which caused public discussion. This process was captured by Yang Jiaqi (Wang Luodan), an intern reporter from a TV station, with her mobile phone. Jiaqi quickly handed the news on the bus to her future sister-in-law Chen Ruoxi (Yao Chen). With the keen sense of smell of the news editor, Ruoxi maliciously magnified the news, which triggered a social search and collectively condemned Ye Lanqiu's moral degradation. In the gap between public accusations and the arrival of the disease, Ye Lanqiu took the 1 million yuan lent to her by her boss Shen Liushu (Wang Xueqi) and completely disappeared. Unexpectedly, this made her be called a "mistress". Ruoxi's boyfriend, a photographer, was accidentally drawn into Ye Lanqiu's world. In order to get a high salary, he was hired to accompany Ye. But he never thought that this would be the last time in the life of this woman who was blamed. Ye Lanqiu's suicide completely overturned Chen Ruoxi's love and life, and made everyone start to reflect...