Driven by Masaru Okamura (Katsunori Takahashi), L&P Hospital, which relies on donations from large companies to purchase the most advanced equipment and recruit outstanding talents, is growing stronger and stronger. It provides space for new medical talents to show their talents, but at the same time, in order to make profits, it also tries every means to drive away patients who will not bring economic benefits. On the other hand, many local hospitals are squeezed by L&P Hospital and are on the verge of bankruptcy. Sakurai General Hospital is one of these small hospitals that are struggling. The director Sakurai Shuzo (Hira Mikijiro) was originally prepared to accept the injection of L&P Hospital, but the timely return of his beloved disciple Asada Ryutaro (Sakaguchi Kenji) rekindled his hope. Adhering to the supreme concept of considering patients, Ryutaro successively found excellent doctors such as Kato Akira (Izumi Inamori), Ijuin To (Teppei Koike) and Arase Monji (Takashi Abe) who were calculated by their peers, and formed a strong medical team. The battle of small and big is also the struggle between faith and material desire...