Fry is a deliveryman living in the 20th century. He is unhappy with his work and life, and is a complete loser. By chance, he was sent to the future 1,000 years later by a time machine, that is, the year 3000 AD! In the bizarre future world, he met Leela, a one-eyed female alien. Leela wanted to implant a career chip in him so that he could live in the future, and his new career was also a deliveryman. Fry fled and met the robot Bender on the way. In the process of chasing them, Leela also gave up her disliked career and became a professional fugitive together with Fry. The three of them boarded an interstellar spaceship and became crew members of the Interstellar Express Company. Fry's new job was to deliver express to various places in the universe, that is, he was still a deliveryman. In this way, the deliveryman Fry, Captain Leela, and the robot Bender shuttled through the universe and embarked on a fun and interesting adventure of interstellar express delivery in the 31st century.