Unemployed Fan Guosheng (played by Lau Ching Wan) brutally killed his wife (played by Michelle Ye), which shocked the whole of Hong Kong. He was subsequently diagnosed with mental illness and escaped legal sanctions. Medical talent Zhou Mingjie (played by Huang Xiaoming) took the initiative to be Fan Guosheng's attending physician and tried his best to help him with treatment. Three years later, Zhou Mingjie tried his best to ensure that Fan Guosheng was discharged from the hospital and returned to society, which was unanimously opposed by the medical community, but Zhou insisted. However, new drug dealer murders followed one after another, and the police once again targeted Fan Guosheng. At the same time, Zhou Mingjie's fiancée Baoer (played by Fiona Sit) was threatened with death, and the strong pressure made Zhou Mingjie unable to breathe. How to save your lover and save your career? What is the truth? Can mental patients be cured? A new round of self-salvation quietly begins.