Super escort Frank Martin (Jason Statham) recently worked to pick up Jack, the youngest son of drug enforcement officer Mr. Billings. Frank and Jack and his mother got along harmoniously, but the sudden appearance of a group of gangsters broke the peace. Frank successfully escaped from danger in his first fight with them in the hospital, but for Jack's safety, Frank had to send the child to the other party, and was therefore identified as a kidnapping suspect by the police. Frank found that this kidnapping had a deeper meaning. The drug trafficking group behind the planning of this incident intended to infect the deadly virus to the senior officials of drug enforcement organizations from various countries attending the international conference through Jack, so as to clear the obstacles for their own criminal behavior. Frank took on the trust of Jack's mother Audrey. In the pursuit of the police and the drug trafficking group, he gradually approached the mastermind behind the scenes, Gianni (Alessandro Gassman), and started a series of battles with Gianni, who was also extraordinary.