Xiong Dun (Bai Baihe), a young cartoonist who is about to celebrate her 29th birthday, has suffered blows that ordinary people can hardly imagine. She was fired from her job, her boyfriend bounced her payment, and she went to the police station for no apparent reason. To make matters worse, she suddenly fainted at a party, and after a checkup, she found that something was wrong with her body. Xiong Dun, who has always been optimistic and cheerful, was not frightened or defeated by the disease. She laughed and ridiculed the people and things around her, and looked at the handsome Dr. Liang (played by Daniel Wu) with a face full of love. Most importantly, she is in adversity and has the full support of her parents (played by Li Jianyi and Liu Lili) and Xia Meng (played by Li Yuan) and other friends. No matter where she goes, Xiong Dun will never be lonely and will not give up... This film is adapted from the comic of the same name created by the late cartoonist Xiong Dun based on his own experience.