The curator of the Louvre Museum was murdered in the Louvre. Before he died, he left behind terrifying symbols, which alarmed Robert Langdon (Tom Hanks), a symbol expert. In the process of solving the case, Langdon met the granddaughter of the deceased, Sophie (Audrey Tautou). The two of them encountered danger several times and survived a narrow escape, and gradually developed a love for each other. As the case deepened, they gradually discovered that there was a huge secret behind this murder, and even implicated a mysterious organization that had been hidden for many years - the Priory of Sion. Langdon followed the clues and found that all the decrypted codes were hidden in Leonardo da Vinci's works. The most shocking thing was that Sophie's life experience became complicated for a while. Who is she? What purpose does the Priory of Sion want to achieve by reappearing in the arena?