In New York in 2044, the villain Langge colluded with alien evil forces to try to destroy the earth. A large number of aliens invaded through a mysterious portal and turned the city into ashes. Although the Ninja Turtles fought hard, they were still defeated by the enemy's offensive and suffered heavy casualties. With the strongest weapon of ninjas - hope, the Ninja Turtles decided to go back to the past time and space to find the key to open the portal, stop Langge, and restore world peace. Leonardo's apprentice Casey took on this mission. He successfully contacted female reporter April O'Neill in the past time and space, and joined the Ninja Turtles Leonardo, Michelangelo, Raphael, and Donatello to start the action of saving the world. "Our future, we decide for ourselves" The Ninja Turtles launched the ultimate challenge to Langge.