In 2007, Dr. James studied bionic humans with the support of a Peninsula arms dealer. During the research, the bionic human Andre mutated and went on a killing spree, killing the Peninsula arms dealer, controlling his organization and taking over the research on bionic humans. Dr. James escaped by chance and had to seek protection from the police. Agent Lin Dong (played by Jackie Chan) had to leave his dying daughter Xixi and accept the witness protection mission... Thirteen years later, the publication of a science fiction novel "Blood of the Machine" led to the Black Bionic Human Organization, the mysterious hacker Li Sen (played by Luo Zhixiang) (the son of the murdered Peninsula arms dealer), and the anonymous Lin Dong. The three forces began to approach the life of an "ordinary" girl Nancy (played by Ouyang Nana) and wanted to get the secrets of her. Andre, who had been injured and hidden for many years behind the scenes of the black-clad man, also took action again and finally captured Nancy after many struggles. Lin Dong and Li Sen had to risk their lives to rescue him. At the critical moment, they discovered that Li Sen was actually the son of the murdered Peninsula arms dealer, and the experimental records of the cyborg also fell into Li Sen's hands...