Marty (Woody Harrelson) and Rust (Matthew McConaughey) are a pair of partners who have worked together for many years. Marty is cheerful and smooth, and he is very popular among his colleagues in the police station, while Rust is just the opposite. He is withdrawn and taciturn, immersed in his own world. However, what Marty admires very much is that Rust has extremely sharp and powerful observation, judgment and logical reasoning ability. Many difficult and complicated cases can be easily resolved once he passes through his hands. Although Marty is the only one who can stand Rust, the cooperation and friendship between the two still have irreparable cracks, and the reason is attributed to a mysterious and strange religious murder case that occurred in 1995. Now it is 2012. When the two people who have no contact for a long time come together again because of this case, what kind of truth will be waiting for them?