Henry (Ioan Gruffudd) is the most famous forensic doctor in New York City. His reputation is well-known to his peers in the industry. Although everyone knows Henry's outstanding academic achievements, no one knows that Henry has actually lived for 200 years. An accident has forever taken away his right to die. The long years have also made Henry feel extremely tired and only want to be relieved. Henry works in the morgue. He deals with the dead all day long and just wants to study the ultimate secret of death on these cold corpses. Joe (Alana De La Garza) is a shrewd and capable New York policewoman and Henry's partner. Joe's existence is Henry's only hope and pleasure in this boring world.