Feng Weifeng (played by Deric Wan), an expert in cancer drug research and development, inherited his uncle's luxurious villa and lived with his mother, wife, daughter and uncle's old housekeeper. But since moving into the villa, a series of incredible things have happened. His wife Ailing (played by Yang Si) was often awakened by strange sounds and shadows late at night, and his daughter Jiajia disappeared mysteriously. Soon someone called and claimed that Jiajia had been kidnapped, but the family did not dare to call the police and only asked their friend Chen Yong (played by He Gang) to help investigate. At this time, Feng Weifeng received another anonymous call. Someone wanted to pay a large sum of money to buy his new drug formula, but he flatly refused. After an in-depth investigation, Chen Yong found that everyone in the family was suspected. It can be said that there was a case within a case, and it was full of mystery. But the final result was completely beyond his expectations...