Wuornos (Charlize Theron)'s unfortunate childhood pushed her into a life of sin. Her mother left her and treated her with endless abuse and beatings. Wuornos began a life of prostitution in her teens to satisfy her drug addiction and livelihood. She provided low-level sexual services to drivers on the road, and her hopeless life was endless. However, the appearance of the young girl Sylby (Christina Ricci) made her heart bright, and the two began a relationship and lived together. Sylby's great demand for money made Wuornos willing to run around to make money for her lover. She went to interview several jobs, but was rejected because of her lack of knowledge and rude masculine personality. She could only go back to her old job and met a perverted prostitute on the road. She killed him in anger and took away his money and car. From then on, Wuornos began to commit crimes frequently and became a ruthless female devil on the road.