Xia Zheng (Wang Bojie), the attending physician of the hospital's thoracic department, who finished his work hastily and just wanted to rush home to rest, was urgently recalled after leaving the hospital because of an emergency patient who was seriously injured in a car accident. Xia Zheng's patient, Jin Youzhong (Xue Shiling), who is also a gossip media reporter, heard that an unknown virus had broken out in major hospitals. In order to dig out exclusive information, he actively wanted to find the source of infection and tried every means to be hospitalized; on the other hand, male nurse An Taihe (Zeng Jinghua) and intern doctor Li Xinyan (Xiang Jieru) are passionate medical staff who love each other. They are very enthusiastic about their work and stay in the hospital for several days. When the virus broke out, they not only encountered an unwarned closure of the hospital, but also faced the hearts of people being devoured. In a situation where everyone is likely to be infected with the virus, should doctors, reporters, and medical staff protect themselves or save people? And survive in this gradually falling apart hospital, system, and people's hearts?