In order to allow Kate (Sofia Vassilieva), who suffers from leukemia, to survive, her parents "created" a little daughter, Anna (Abigail Breslin), who has a perfect genetic match with Kate through genetic technology. Anna feels that she is just a "medicine jar" for her sister Kate. For 11 years, whenever Kate needs it, whether it is umbilical cord blood, white blood cells, liver cells, or bone marrow, she has to provide Kate with a steady supply. However, even with a desperate mother (Cameron Diaz), a helpless father, and the love of everyone around her, Kate's condition is getting worse and worse. The failure of her kidney function requires Anna, who is only 11 years old, to donate one of her kidneys. This time, Anna chose to refuse, and found lawyer Campbell to take her mother to court. She wanted to defend her body. However, in court, her brother Jesse revealed another truth... This film is adapted from the novel of the same name by Jodi Picoult, the contemporary bestseller queen of the United States.