The protagonist of the story is a wolf named White Fang (voiced by Nick Offerman). It has grown up in a world where the strong prey on the weak and have long been accustomed to the intrigues and deceptions. After growing up, his mother brought White Fang back to his master, a kind and strong Indian. In this way, White Fang got a job pulling a sled, and the days passed in peace day by day. However, the tight economy forced the owner to sell White Fang to a man named Smith. Smith was full of bad water and had no kindness at all. He only thought about how to squeeze profits. Under Smith's training, White Fang became a fighting wolf and exchanged his blood for money for Smith. Fortunately, White Fang soon met his new master Scott, who gradually healed White Fang's injured heart with love and care.