The days of the five girls on the 22nd floor accompanying each other continue, and more difficulties are coming one after another. Fortunately, they already know each other well enough, and their feelings are becoming increasingly deep, so they can support each other to overcome these difficulties. While Ye Zhenzhen is immersed in scientific research, she is frequently affected by David's family affairs. How to live a simple life has become a problem. Fortunately, she is firm and sober enough, and has a family that loves her enough, and finally solves these difficulties. Fang Zhiheng unexpectedly gained a younger sister, which made her change a lot and gradually return to the right track of life. Zhu Zhe has gained a firm foothold in Shanghai completely on his own through years of struggle and accumulation, and finally broke through the bottleneck of his career. After taking a detour, He Minhong left the 22nd floor and finally returned. He began to learn to think, know how to give, and understand how people should get along with each other. Yu Chuhui relied on external motivation to force himself to work hard, gradually becoming self-conscious, steadily rising, and getting rid of the shackles of his background. The tests and gifts given by life will continue, but with the support and company of the sisters on the 22nd floor, they can move forward bravely and run towards happiness all the way.