Li Xiaoyu's peaceful life was broken by his act of covering up Qiu Yongbang's cheating. The casino owner was murdered, and Li Xiaoyu was arrested as the biggest suspect. His girlfriend Wenwen, a flat model, was kidnapped by the traffickers of the Horez Gang. Li Xiaoyu, who was unable to escape for a while, asked Qiu Yongbang to help find Wenwen, but he didn't know that the people who kidnapped Wenwen were Qiu Yongbang and his gang. After knowing the truth, Li Xiaoyu caught up with the Chinese tourist bus where Qiu Yongbang was as a police informant. The bus had been hijacked by Qiu Yongbang and his gang. In order to find Wenwen and save a car of Chinese compatriots, Li Xiaoyu stayed on the bus despite Qiu Yongbang's dissuasion. In order to avenge her mother, surgeon Jane followed her biological father Hong Yinhe and got on the bus. The witty and brave Jane became Li Xiaoyu's best partner. The two worked together to save a car of hostages and find Wenwen. The reason why Qiu Yongbang was helplessly controlled by the Horez Gang also surfaced. Qiu Yongbang obtained Li Xiaoyu's forgiveness, and the brothers worked together to go to the US-Mexico border, and finally assisted the police in destroying the Horez Gang and rescuing more innocent people. After a seven-day life-and-death journey, the broken brotherhood and father-daughter relationship were redeemed.