A real-life adventure live game called Nerve is sweeping New York City. Game participants have two different choices, either to be a "viewer" or a "player". Viewers pay to decide whether players will challenge various adventure games. High school girl Vee (Emma Roberts) is an ordinary good girl. Her biggest pleasure on weekdays is to "peep" at JP, the male god in school. Her friend Sydney is addicted to this live game and makes all kinds of bold moves to attract viewers. Influenced by it, Vee, who is used to being a bystander on weekdays, also joined this live game and became a "player". Her first adventure is to kiss a stranger. After the challenge was successful, she discovered that this stranger Ian (Dave Franco) is also one of the game players. Their big adventure live broadcast, from the beginning of fun and excitement, gradually went out of control. They must work together to escape this life-threatening live broadcast...