In a cemetery in the suburbs of Rome, workers who were renovating the cemetery accidentally dug up a coffin that had been buried for more than 200 years, and a mysterious box was unearthed along with the coffin. This discovery gave the priest present an ominous premonition, and he ordered the workers to rebury the coffin and mail the box to Mike Pierce (Adam James), the curator of the History Museum, asking this old friend who studies the occult to help conduct an in-depth investigation. However, the box was rashly opened by Mike's assistant Giselle (Coralina Cataldi-Tassoni) and Mike's girlfriend Sarah (Asia Argento), and an evil witch who had been imprisoned for hundreds of years returned to the world... The final chapter of director Dario Argento's "Mother Trilogy" (the first two parts were "Suspiria" and "Inferno").